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Synonym(s) HP-β-CD
Catalog number rsc001
CAS Registry number 128446-35-5
MDL number: C42(H)70-nO35(C3H7)n
EINECS number: 2354.64614
Molecular Formula White powder
Formula Weight ≥98.0%
Specification

mp 278°C(dec.)

Hazard Symbol 25kg/drum
Risk Phrases
Safety Phrases
Transport information
Price & Availability
Production scale
Application

Product description:


Characteristics and usage:

Introduction of Hydroxypropyl (s) into the molecular of beta-Cyclodextrin hydrate breaks inner annular hydrogen bond and thus it increases the water solubility of beta-Cyclodextrin hydrate without breaking its molecular cavity.

In food and spice industry, HP-β-CD can increase stability and shelf-life of nutrient molecule, can cover or rectify unpleasant smell or taste of nutrient molecule. HP-β-CD has good water solubility, if the degree of substitution (DS) is greater than 4, it will be miscible with water, 50% ethanol and methanol water solution.

In cosmetic industry, it acts as stabilizer, emulsifier, and odor remover. It can reduce the irritation to skin mucosa tissue cause by organic molecule in the cosmetics.

In pharmaceutical industry, because of its low surface activity and hemolytic activity, it is an ideal solubilizer for injection or pharmaceutical excipient. It can improve water solubility of pharmaceuticals that disinclined to dissolve in water. It can improve stability, bioavailability and efficacy of pharmaceuticals. It can also adjust or control release rate of pharmaceuticals to reduce their side effects. It can be used in oral drugs, injections, mucosal drug delivery system (including nasal mucosa, the rectum, the cornea), transdermal drug delivery system, vehicle for lipophilic targeting drugs, also as protective agent and stabilizer for protein products.

【技术指标】

外观 Appearance

白色粉末 White powder

水中溶解度

Solubility in Water25℃,g/100ml

≥75

干燥失重(%Loss on drying

≤5

炽灼残渣(%Ignited Residue

≤0.5

β-环糊精残留量(%Residual β-CD

≤1

重金属Heavy Metalsppm

≤10

丙二醇(%Propylene Glycol

≤1

环氧丙烷残留量

Residual Propylene Oxideppm

≤ 1

平均分子取代度(MS

4-7